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Glioblastoma (GBM). GBM is the most Sauron Eye Ugly Christmas Sweater Xmas Gifts and most aggressive brain cancer. It’s highly invasive, which makes complete surgical removal impossible. And because of the blood-brain barrier (BBB), it doesn’t respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called “the Whipple procedure”. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.
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Geography. Pick the local team. If you are in say Miami, congratulations you can be a Dolphins fan and if you want to support teams across several levels, then the Dolphins for the NFL, Miami Hurricane among the power college programs and Florida International Panthers in the so-called Group of 5. If you are in an area not near an NFL team pick a Sauron Eye Ugly Christmas Sweater Xmas Gifts college and could even find enjoyment following a small regional team that plays in Division II or III or Division I FCS.
Christmas begins at midnight on the Sauron Eye Ugly Christmas Sweater Xmas Gifts of 24 December (the beginning of 25 December). One should not begin putting Christmas decorations up until Christmas Eve. Christmas Day lasts a full eight days, and ends on the first of January – the Octave Day of Christmas. The season of Christmas lasts until Epiphany on the 6 of January, so your decorations should stay up[ that long, and the Christmas Marian antiphon gets sung until the first of February, so you may take your Christmas decorations down at the end of January. Please, please, please do NOT put Christmas decorations up during Advent. Advent is the Penitential season which encompasses the four Sundays before Christmas, so it begins right around the end of November. To repeat, Advent is a PENITENTIAL season, so nothing of Christmas should intrude on Advent other than preparation – spiritual preparation for Christmas, going to confession each Saturday, saying extra prayers, going to daily Mass, etc. All would be excellent preparations for Christmas, but do NOT start celebrating Christmas itself until midnight at the beginning of 25 December!