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Glioblastoma (GBM). GBM is the most Merry Smeggin’ Christmas Red Dwarf Ugly Christmas Sweater and most aggressive brain cancer. It’s highly invasive, which makes complete surgical removal impossible. And because of the blood-brain barrier (BBB), it doesn’t respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called “the Whipple procedure”. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.
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In terms of skills it depends what position they are moving from and to, but I think a season of training with a pro side and some regional amateur rugby games in the lower leagues followed by 1-2 seasons playing below the top flight would be required, if they had the right attributes to reach the top flight. It could be 2 years in total for a winger, or 4 for a more involved position with higher technical and tactical requirements. A player with exceptional physical attributes like being able to run a sub-11 second 100m at 275lbs and a lethal side-step or being fit at 300lbs and immensely strong and Merry Smeggin’ Christmas Red Dwarf Ugly Christmas Sweater explosive might make it earlier as their attacking threat with the ball in hand would do more to cancel out their shortcomings than a more physcially average player.
I guess there are a lot of Merry Smeggin’ Christmas Red Dwarf Ugly Christmas Sweater Christmas decorations – I just never think of them from that poin of view. I seem to think and I value Christmas decorations through their meaning and my traditions, not their prettiness. My traditions are a mixture of the Finnish and general North European traditions, mostly from Sweden and Germany, I think. In general, Christmas isn’t called Christ Mass here. We talk about it by the old Norse? word Yule. That’s Joulu in Finnish. I think that’s important. The name doesn’t refer to any Christian features and it’s pretty easy to celebrate Joulu without any particularly Christian context under that name. I value quite simple decorations that I feel some kind of connection with. The christmas tree is a must. It isn’t very old tradition in Finland, but it’s a very natural decoration that was easy to adopt. (There is an ancient tradition to decorate houses with small birches in Midsummer, so a christmas tree feels like a good equivalent in the winter).