Design Iration August 23 24, 2024 Daytrippin In Paradise Pacific Amphitheatre, Costa Mesa, CA Poster Shirt
Glioblastoma (GBM). GBM is the most Design Iration August 23 24, 2024 Daytrippin In Paradise Pacific Amphitheatre, Costa Mesa, CA Poster Shirt and most aggressive brain cancer. It’s highly invasive, which makes complete surgical removal impossible. And because of the blood-brain barrier (BBB), it doesn’t respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called “the Whipple procedure”. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.
Design Iration August 23 24, 2024 Daytrippin In Paradise Pacific Amphitheatre, Costa Mesa, CA Poster Shirt
Dean gets to their motel and Sam’s dressed it all up, even though he spent much of the Design Iration August 23 24, 2024 Daytrippin In Paradise Pacific Amphitheatre, Costa Mesa, CA Poster Shirt not wanting to celebrate. They share some jokes for the rest of the episode, clearly trying not to get teary-eyed or reminisce too much about their…well, mostly shitty lives. They share some presents, express some gratitude, drink some eggnog, and watch a game on TV. Smiling and enjoying each other’s company. I love this episode and it goes down as my favorite Christmas story because the writers did not hold back on making it bittersweet as fuck. These two poor sons of bitches have almost nothing at all – they’re sitting in a cheap motel, both their parents are dead, Dean is going to be dragged to Hell for eternity within the year, and the only reason they wake up in the morning to save other people is because they literally cannot do anything else now that they’ve been hunting for so long.