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Beethoven turns his anger to Fate at having been dealt a Santa Claus With Reindeer Cow For Unisex Ugly Christmas Sweater and now, this decision. In consolation, Fate allows Beethoven to travel back through his life in order to review it and make any changes that he wishes. Beethoven accepts this and they begin with Beethoven’s experiences as a child. Beethoven comes into his room while the young Beethoven has just been slapped by a tutor for failing to receive appointment to the Imperial Court. Beethoven turns to Fate and informs her that he did not need the hardships that he had faced, with his mother dead and a painful childhood. He requests that she remove the experience from his life. After being told that such a request would remove the inspiration for his sixth symphony, he changes his mind. Fate and Beethoven then go to one of Beethoven’s happier moments, meeting the composer Wolfgang Amadeus Mozart in the city of Vienna. Fate then reminds Beethoven of his “immortal beloved” Theresa and after experiencing a fond remembrance, Beethoven explains his reasons for needing to leave her.
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Glioblastoma (GBM). GBM is the most Santa Claus With Reindeer Cow For Unisex Ugly Christmas Sweater and most aggressive brain cancer. Itās highly invasive, which makes complete surgical removal impossible. And because of the blood-brain barrier (BBB), it doesnāt respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called āthe Whipple procedureā. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.